November 21, 2010

New Cholesterol Drug Increases HDL and Lowers LDL

Posted in Heart Disease in the News, Heart disease tips tagged , , , , , , , at 2:34 am by keepyourhearthealthy


photo by Suat Eman

For several years now, the drug companies have been trying to discover the ultimate drug to increase HDL.


It’s just not that easy to increase your good cholesterol (HDL) with prescription drugs.  Right now, niacin is the best way to increase HDL but it has the significant drawback of skin flushing.  People who take niacin at first feel very hot and their skin may turn red like a temporary sunburn.

Given all the problems with niacin, a new class of drugs to increase HDL have been attempted on several occasions.  One of these new drugs has finally passed the phase 3 trials and may actually go on to FDA approval in the near future.  Anacetrapib is being manufactured and tested by Merck for treating dyslipidemia (high bad cholesterol and low good cholesterol).  The studies so far are quite promising but many are weary.  Pfizer had a similar drug being tested in the same class of drugs but Pfizer’s drug was taken out of testing due to significant problems.

Cardiologists all over would love to have a better option for treating low HDL.  Right now though, we can only wait and see how the remaining trials work out for this promising new drug!

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