February 9, 2011

Important New Information For Pradaxa Patients

Posted in Heart Disease in the News, Heart disease tips tagged , , , , , , , , , , at 1:04 pm by keepyourhearthealthy

photo from Pradaxa press release

Patients who receive their Pradaxa in a bottle are under a new advisement this week.

Many heart-savvy people have heard about a unique new drug called Pradaxa.  This ground-breaking drug burst into the pharmaceutical market in record time after gaining FDA approval late last year.  Pradaxa is famously known for being unique given that it is the ONLY alternative to Coumadin (warfarin) in terms of preventing strokes for the atrial fibrillation population.

Undoubtedly, thousands of patients have already made the switch from Coumadin to Pradaxa.  What many of these patients may not realize though is that Pradaxa is unique in another important way.  Pradaxa pills sold in a bottle are considered “expired” after only 30 days. The capsules are easily effected by humidity so the manufacturer recommends using all the medication within 30 days of opening the bottle.

A 30-day expiry is very unusual given that the standard expiry for most medications is 1 year.  Some pharmacists have returned their bottles to the manufacturer and requested blister packs instead.  Blister packs are sold in Europe and keep each pill individually wrapped, thus safe from the humidity.

In case you are a new Pradaxa user, it is important that you wait until the last minute to open the bottle.  You should also avoid having more than one bottle open at a time.  If you tend to store your pills in 2 different locations (ie. one at work and one at home), you’ll need a different routine for Pradaxa. The Pradaxa bottle has a special lid which keeps the drug stable so you should avoid putting the capsules in a different bottle. The safest place for the pills is inside the manufacturer’s bottle and the pills still expire within 30 days of opening.

January 13, 2011

The New Coumadin Alternative…What Do Patients Think About It?

Posted in Heart disease tips, Helpful Heart Links, Uncategorized tagged , , , , , , , , , , at 11:47 am by keepyourhearthealthy

image by Idea go

Pradaxa is certainly ideal when you look at how it compares to Coumadin on paper.

Pradaxa is a breakthrough Coumadin alternative that prevents more strokes than Coumadin, does not require fingerstick monitoring and has almost no major interactions with food or other drugs. It sounds like a dream come true for atrial fibrillation patients everywhere who despise Coumadin!

Now that Pradaxa is readily available to patients, what do they think? Is it the amazing new drug that many have expected it to be?  Some say “yes” and some say “no.”  One Pradaxa user posted their experience with the drug on a Pacemaker Club website online and stated they “love the convenience.” Others on the same website complained that it did not work out for them.

The biggest obstacles for many are just what Pradaxa’s manufacturer expected: price and heartburn.  First, many people have to get over the sticker-shock of paying $40 to $250 per month.  Then there’s the common side effect of heartburn.  20% of patients discontinue Pradaxa because it upsets their stomach.

One patient I spoke to stopped it because the heartburn and nausea were intolerable after a few days of switching to Pradaxa.  She eventually switched back to Coumadin and resumed her routine INR checks.  In my opinion she was more likely to get heartburn on the Pradaxa because she also suffers from a large hiatal hernia (a condition where part of the stomach is squeezed up through the diaphragm) which causes problems with acid reflux.  Pradaxa’s manufacturer has already launched a defensive campaign in order to help patients work through problems related to the drug.  Their website www.pradaxa.com offers a support program which includes a hotline and a savings card.  I personally registered for the support program over 2 weeks ago and have yet to receive a response.  Maybe they have a few kinks to work out?

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